: As of April 23, 2026, medical cannabis is no longer subject to Section 280E of the Internal Revenue Code. This allows companies to deduct normal business expenses, potentially unlocking $1.6B to $2.2B in annual after-tax cash flow for the industry.
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: Retains ~60% of cash from operations and operates over 100 dispensaries across 14 states. Trulieve Cannabis Corp. (OTC: TCNNF)
: Consistently profitable since 2020 with a vertically integrated business model.
: Dominant market leader in Florida, Arizona, and Pennsylvania with over 230 retail stores.
AdvisorShares Pure US Cannabis ETF (MSOS) or YOLO for broader exposure
: Recently reported record net revenue of $210 million and achieved net income profitability in Q1 2026. Turning Point Brands, Inc. (NYSE: TPB)
: Particularly benefits from the removal of the 280E tax burden, which previously hindered its operating cash flow. Tilray Brands Inc. (NASDAQ: TLRY)