The Murder House remains the most iconic location in the franchise. It has reappeared in later seasons, most notably:
A fractured family trying to heal from infidelity and miscarriage. The Murder House - American Horror Story
Characters return to the house to uncover the origins of the Antichrist. The Murder House remains the most iconic location
The season follows the Harmon family—Ben, Vivien, and their daughter Violet—as they move from Boston to Los Angeles to escape a painful past. They unknowingly purchase a house inhabited by the ghosts of its former residents. Key Characters The Murder House - American Horror Story
The house itself seems to "want" things, often driving residents to madness or violence. Historical Inspiration
The resident housekeeper who appears differently to men and women. The House Rules