Sgk1 | 4 Zip

: The human SGK1 protein is a serine/threonine-protein kinase consisting of 431 amino acids with a molecular mass of approximately 49 kDa . It features an N-terminal PX-like (phox homology) domain, a central catalytic kinase domain, and a C-terminal hydrophobic motif.

SGK1 acts as a "hub" molecule regulating diverse cellular processes: SGK1 4 zip

: It inhibits apoptosis by phosphorylating and inactivating pro-apoptotic factors like FOXO3a and p53 . : The human SGK1 protein is a serine/threonine-protein

phosphorylates Serine 422 at the C-terminal hydrophobic motif. a central catalytic kinase domain