[s4e16] House's Head (part 2) May 2026

: House’s subconscious manifests a guide who prompts him to identify the patient. He eventually realizes her necklace is made of amber, signifying that the "dying patient" is actually Amber Volakis , Wilson’s girlfriend.

: The finale fundamentally alters the series' core relationship. Wilson is left alone, finding a final note from Amber, while House awakens from a coma to face the wreckage of his friendship. [S4E16] House's Head (Part 2)

The finale begins with House suffering from retrograde amnesia following a bus accident. Convinced he witnessed a life-threatening symptom in a fellow passenger before the crash, House undergoes increasingly dangerous procedures—including hypnosis and deep brain stimulation—to retrieve the lost memory. : House’s subconscious manifests a guide who prompts

In the second part, "Wilson's Heart," the team discovers Amber is suffering from multisystem organ failure. Wilson is left alone, finding a final note