Pearlcam -

The subject is placed in the imaging chamber. PearlCAM software captures the NIR signal and overlays it on a standard grayscale "white light" image for anatomical context.

💡 Many researchers prefer the Pearl system because it uses a One-Touch imaging approach—eliminating the need for complex camera adjustments and making the technology accessible even to those without a background in physics.

Researchers use PearlCAM to test new "smart" dyes that attach specifically to cancer cells. By viewing the animal through the Pearl system, surgeons can practice identifying tumor margins that would be invisible to the naked eye. Washington University has utilized this for foundations in translational imaging. 2. Drug Delivery Tracking PearlCAM

PearlCAM is the proprietary interface used to capture and analyze high-resolution images in the spectrum. Unlike visible light, NIR light can penetrate several centimeters into biological tissue, allowing for:

The software quantifies the signal intensity, allowing researchers to say exactly how much of a drug reached the target compared to healthy tissue. 🌟 Why It Matters The subject is placed in the imaging chamber

Because the imaging is non-invasive, researchers can scan the same animal over days or weeks. This reduces the number of animals needed for a study and provides a more accurate timeline of how a tumor grows or shrinks in response to treatment. 🛠 Features and Workflow

High-sensitivity detection of signals from within internal organs or deep-seated tumors. Researchers use PearlCAM to test new "smart" dyes

A fluorescent probe (like IRDye®) is injected into the subject.