: Co-invented infinitesimal calculus (sharing credit with Leibniz) to describe rates of change.
: Philosophiæ Naturalis Principia Mathematica (1687) is considered the seminal work of the Scientific Revolution. 2. Isaac Asimov (1920–1992)
Regarded as one of the most influential scientists in history, Newton laid the foundations for modern physics and mathematics during his "miracle years" (1665–1666).
A prolific American author and biochemistry professor, Asimov was one of the "Big Three" science fiction writers.
: Formulated the Three Laws of Motion and the Law of Universal Gravitation , which explained planetary orbits and terrestrial gravity.