: Suggests Multiple Myeloma or MGUS. Broad Increase : Chronic infection or autoimmune disease. Key Patterns to Look For
Electrophoresis typically reveals five or six distinct peaks: Key Components Clinical Significance of Changes Main serum protein : Suggests Multiple Myeloma or MGUS
: Liver disease, kidney loss (nephrotic syndrome), or malnutrition. Increased : Dehydration. Alpha-1 Alpha-1 antitrypsin Increased : Acute inflammation. Alpha-2 Haptoglobin, Alpha-2 macroglobulin Increased : Acute phase reaction or nephrotic syndrome. Beta Transferrin, Complement Increased : Iron deficiency or high cholesterol. Two peaks ( ) are visible in capillary tests. Gamma Immunoglobulins (Antibodies) Increased : Dehydration
: The JNMG guide on anomalies provides specific indicators for bone pain or unexplained renal failure. Beta Transferrin, Complement Increased : Iron deficiency or
: Access the Cerba laboratory document for standard reference values and capillary electrophoresis details. The Five Main Protein Fractions