Download Cerebral Amyloid Angiopathy Criteria The Next Generation Pdf May 2026

: The minimum age for applying the criteria has been lowered from 55 to 50 years .

: For the first time, white matter characteristics are part of the formal criteria. A diagnosis of probable CAA can now be made with just one lobar hemorrhagic lesion if accompanied by either: : The minimum age for applying the criteria

: While lobar intracerebral hemorrhage (ICH) and microbleeds remain central, cortical superficial siderosis (cSS) and convexity subarachnoid hemorrhage are now prioritized. Multiple separate foci of siderosis can now qualify a patient for a "probable CAA" diagnosis on their own. : The minimum age for applying the criteria

The v2.0 criteria significantly increase diagnostic sensitivity—capturing more true cases without losing specificity—by broadening the biological markers recognized by MRI. : The minimum age for applying the criteria