Critics and viewers have noted that while the film is categorized as a comedy, it is a "multilayered story" that leans into drama, depicting the raw struggle of "wannabe comedians". Some viewers noted that the film's modest initial ratings may have stemmed from audiences expecting a lighthearted comedy, whereas the actual tone is more contemplative and exploratory regarding the nature of humor and success. Comedians (2021) - IMDb

The story follows six aspiring stand-up comedians in Manchester who have spent weeks attending an evening comedy course. The film captures them on the night of their final rehearsal and debut performance at a local club.

They must choose between following the teachings of their mentor—who advocates for "intelligent and uncompromising" comedy that challenges the audience—or tailoring their acts to satisfy the scout's preference for cruder, more mainstream humor.